UK STATISTICS 2020 – Beagles and other Dogs
August 25, 2021
The 2020 Annual Statistics of Scientific Procedures on Living Animals in UK were released by the Animals in Scientific Regulation Unit at the Home Office on 15th July 2021
We have studied the many pages in depth and will attempt to interpret the figures and put them into as simple a format as possible based on Beagles used and for what purpose.
We begin with the number of PROCEDURES on Beagles who were used in the year 2020. This is not the actual number of Beagles used but the number of procedures performed on Beagles.
Procedures on Beagles used in :
Basic Research ………659
TOTAL No. of Procedures performed …..4270
NEXT is the NUMBER of Beagles used for the first time in 2020.
Number of Beagles used in :
Basic research …….41
Translational/Applied Research…. 132
TOTAL No. of Beagles used for the first time….2738
Let’s not forget that further Beagles, already in use from previous years, will still be undergoing procedures as well as those used for the first time.
Of those 2738 Beagles used for the first time:
1942 were born in the UK and
796 in the ‘Rest of the World’
The Home office statistics produced each year include the ultimate SEVERITY of procedures performed on animals. eg The severity is classified under the maximum an animal has reached in the whole of its lifetime — if an animal lives for a year and experiences some mild pain but also, say, 10 minutes of moderate pain, it is classed as moderate severity.
There are 4 classifications :
MILD – Mild procedures include an animal experiencing short-term mild pain such as having an injection. A GA animal being born, never showing any effects of the altered gene they are carrying, never being used in an experiment and then being killed humanely would be counted as a mild procedure.
MODERATE – A moderate procedure involves an animal suffering short-term moderate pain, or longer-term mild pain. This includes procedures like surgery under general anaesthetic.
SEVERE – A severe procedure may cause severe pain, suffering or distress or long-term moderate pain, suffering or distress. This would include experiments where an animal suffers from a debilitating disease and gets sick very quickly, before there is the opportunity for intervening (eg sudden paralysis in stroke models).
NON-RECOVERY – Procedures, which are performed entirely under general anaesthesia from which the animal shall not recover consciousness shall be classified as non-recovery.
In the case of DOGS (mainly Beagles) used in 2020 the numbers of procedures under each heading are :
MILD – 3253
MODERATE – 1013
SEVERE – 9
NON-RECOVERY – 65
Of the 65 NON-RECOVERY – 25 were under the heading ‘Other’, 11 were under the heading ‘Non-Regulatory Use- Toxicology and ecotoxicology’ & 29 were under the heading ‘Blood Based Products’
Of the 9 SEVERE – 6 were used in ‘Repeated Dose Toxicity’ (RDT), 2 for regulatory – efficacy and tolerence & 1 for Pharmacodynamics (the study of how a drug affects an organism)
3 were used for >28 days (RDT)
0 were used for 29-90 days (RDT)
3 were used for > 90 days (RDT)
2 were used for regulatory (efficacy and tolerence)
1 was used for Pharmacodynamics
Many of the MODERATE were under similar headings, as is common with Beagles.
Toxicity testing for the use of human drugs, animal drugs, plant and environment products in the main.
In the table detailing Regulatory Requirment :
2868 procedures were to satisfy EU Requirements
29 to satisfy UK Requirements